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The Knowledge Zone
We are constantly analysing the latest trends and technologies in order to produce whitepapers that can be used by the entire industry. We believe that sharing our insight and knowledge can help to drive the industry forward and promote best practice.
Here, you’ll find details of our latest whitepapers. To access them for free simply fill in the forms within the links below.
Filtration – The Forgotten Process By Noel Quigley
Filtration is often overlooked during the development of new processes, but at what cost? In this whitepaper BPE’s managing director explores how a lack of technological innovation and the overlooking of filtration’s importance within process development is creating a ‘perfect storm’ for inefficiency.
Continuous Reactor Modelling By Noel Quigley and Sam Fass
Plug flow reactors (PFRs) are the current standard within the pharmaceutical industry when developing continuous flow reactions. This paper outlines the importance, however, of applying engineering principles to tailor the correct reactor to your process using advanced process simulation. It looks at how process modelling can be used to test the reaction kinetics and highlight the impact this has on the design of the reactor.
Technology Developments in Aseptic Fill-Finish Operations By Andrew Stevenson
The evolution of filling equipment technology is having a positive ripple effect on efficiency and productivity within the pharmaceutical manufacturing industry. Andrew Stevenson looks at how different types of components have been filled, inspected and packaged historically and how it may be changing.
Dust Explosions By Keith Plumb
The aim of this whitepaper is to provide a description of a rigorous approach to the assessment of the risks associated with dust explosions. It looks at a step-by-step route that includes reducing the inventory of dangerous substances in the workplace, a hazardous area classification, a thorough review of sources of equipment, and full consideration of the severity and consequences of an explosion.
Cell Homogenisation By Gary McRobbie
There are many methods for achieving cell disruption but what are the financial and cost implications? In this whitepaper, Gary McRobbie at BPE, focuses on the efficiency achieved by the standard approaches used for an industrial scale operation.
Understanding Functional Safety and Related Standards By Peter Stabler
Although adhering to functional safety requirements is not a legal requirement, they are widely regarded by regulators as representing best practice and yet companies remain incompliant. This paper highlights that maintaining compliance with the safety standards will help businesses ensure not only the safety of their operations, but also that they are managing their operations effectively.
LOPA & High Containment – The Basis of Safety Methodology By Gary McRobbie
Working with ‘high potency’ biological materials requires the highest levels of integrity and containment. The consequences from a containment breach hazard are very serious. Focussing on biological materials, this whitepaper outlines an approach to meet user risk reduction obligations, using LOPA hazard analysis techniques.