Pharmaceutical

We are proud to be a UK leader in process engineering design for the pharmaceutical industry. With more than two decades’ experience in the sector, we have a deep understanding of the unique challenges and opportunities it faces.

Our dedicated pharmaceutical leadership team includes both scientists and engineers, who have considerable experience of both the primary and secondary pharmaceutical sectors. Our team understands the underlying science and the needs of the process and we are used to working closely with research & development functions. Many of our consultants have joined BPE from careers in the manufacturing side of the industry and consequently understand first-hand our clients’ operations, maintenance, safety, GMP and Quality Assurance (QA) needs.

API production

Our process development, scale up and optimisation services have become indispensable for many pharmaceutical companies, including those developing APIs. We have worked on countless projects involving both batch and continuous processing and our focus is to deliver practical solutions that maximise the available return on investment (ROI) for both capital and operating costs.

We have a thorough working understanding of PAT (Process Analytical Technology) and we can apply unrivalled experience to projects ranging from simple equipment replacement through to full facility design. Our excellent knowledge in regulatory compliance means we can fully support with commissioning and validation too. Among our other specialist areas of expertise in the pharmaceutical sector are:

Oral solid dosages

  • Granulation
  • Blending
  • Vacuum transfer systems
  • Drying
  • Tablet compression
  • Tablet film coating (fluid bed etc)
  • Encapsulation

Oral liquids and topicals

  • Non-sterile liquids
  • Creams and ointments

Large and small volume parentals

  • Dispensing
  • Mixing
  • Filling/Transfer
  • ‘Paperless’ and highly automated facilities
  • Depyrogenation & sterilisation

Sterile filling

  • Advanced Aseptic Process (AAP) Technology Options
  • Freeze drying
  • High speed filling, stoppering & capping
  • IPC & environmental monitoring
  • Barrier selection

Inhalations

  • Utilisation
  • Process optimisation

Medical devices and diagnostics

  • Optimisation (wash and sterilisation cycles etc)
  • Solvent recovery

Facility support

  • Clean room design
  • Clean utilities (Steam, purified water, DI water & Medical gases)
  • Barrier isolation and containment technologies
  • Clean-in-place (CIP) systems
  • Packaging
  • Process automation & advanced process controls
  • Application of process analytical technology (PAT)
  • Process intensification, optimisation & scheduling
  • Regulatory compliance, commissioning and validation services

Read about how we helped a pharmaceutical manufacturer take its bench-scale process to a semi-automated plant.